Nouvelles publications - Last publications

  • TIRAP 180L Single Nucleotide Polymorphism is Associated with Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children

Johan N. Siebert, Lutz Hamann, Charlotte M. Verolet, Cécile Gameiro, Stephane Grillet, Claire-Anne Siegrist, Klara M. Posfay-Barbe

Published in Frontiers in Immunology, section Microbial Immunology.

This publication relates to a research project undertaken by the Paediatric Clinical Research Plateform:


  • Time-To-Positivity of blood cultures in children with sepsis

Alexa Dierig, Christoph Berger, Philipp K. A. Agyeman, Sara Bernhard-Stirnemann,  Eric Giannoni,  Martin Stocker,  Klara M. Posfay-Barbe, Anita Niederer-Loher,  Christian R. Kahlert, Alex Donas, Paul Hasters, Christa Relly,  Thomas Riedel,  Christoph Aebi,  Luregn J. Schlapbach, Ulrich Heininger and the Swiss Pediatric Sepsis Study

Blood cultures are essential for the diagnosis and further appropriate treatment in children with suspected sepsis. In most hospitals, children will be empirically treated or closely monitored for at least 48 h awaiting results of blood cultures. Several studies have challenged the optimal duration of empiric treatment in the era of continuously monitored blood culture systems. The aim of our study was to investigate time-to-positivity (TTP) of blood cultures in children with proven sepsis.